Scientist / Senior Scientist, Assay Development

Job Description

Job Description

The Role

We are seeking a highly motivated and creative Scientist/Senior Scientist in Assay Development. This individual will play a critical role in developing and commercializing protein assay kits. While direct experience in assay development is highly valued, we are equally interested in candidates who demonstrate strong problem-solving skills, intellectual curiosity, and the ability to learn quickly and independently.

Key Responsibilities

• Lead and contribute to the development of bead-based immunoassay kits across the product lifecycle—from feasibility and optimization through verification, validation, and commercialization.
• Design, execute, and troubleshoot experiments involving antibody selection, reagent conjugation, buffer/diluent optimization, and validation across complex biological matrices (e.g., plasma, serum).
• Formulate and optimize buffers/diluents to mitigate matrix effects and improve assay sensitivity, specificity, and robustness.
• Continuously improve assay performance by enhancing sensitivity, dynamic range, reproducibility, and robustness.
• Establish procedures and quality control processes for manufacturing reagents products.
• Accurately document experimental procedures and results in compliance with ISO and good documentation practices.
• Support customer collaborations by analyzing data, writing reports, and presenting findings.

Qualifications

Required

• MS or PhD in life science or related field (e.g., biology, biochemistry, bioengineering).
• 3+ years of experience in assay development in a commercial or translational research setting.
• Strong foundation in immunoassays or bioanalytical methods (e.g., ELISA, bead-based assays, or similar).
• Demonstrated ability to think critically, troubleshoot complex problems, and pay close attention to detail.
• Hands-on experience in laboratory protocols such as ELISA design, optimization, or related immunoassay workflows.
• Experience in addressing matrix effects in biological samples by designing or formulating buffers/diluents.
• Strong motivation to learn and adapt quickly to new technologies and methods.
• Excellent organizational skills with clear, concise communication and documentation abilities.

Preferred

• Expertise in protein chemistry, conjugation methods, and buffer formulation.
• Experience with microparticle-based immunoassays and/or ultrasensitive platform.
• Familiarity with sourcing, evaluating, and working with antibodies and other critical reagents.
• Track record of successful assay optimization for sensitivity and robustness in complex biological samples.

How to Apply

To apply, please send your CV to: hr@genotixbio.com

We offer benefits and equity and are an equal opportunity employer. Salary and equity compensation to be determined based on experience.

Company DescriptionGenotix Biotechnologies is a venture-backed early-stage biotech startup based in Sunnyvale, CA. We are developing innovative immunoassay technologies that expand the boundaries of protein detection while drastically reducing cost and simplifying workflows. Our team is composed of experienced professionals united by the mission to build the next frontier protein detection platform to make advanced diagnostics accessible and impactful. The company is founded by a seasoned entrepreneur with a track record of successful commercialization and exit of diagnostic products.

Company Description

Genotix Biotechnologies is a venture-backed early-stage biotech startup based in Sunnyvale, CA. We are developing innovative immunoassay technologies that expand the boundaries of protein detection while drastically reducing cost and simplifying workflows. Our team is composed of experienced professionals united by the mission to build the next frontier protein detection platform to make advanced diagnostics accessible and impactful. The company is founded by a seasoned entrepreneur with a track record of successful commercialization and exit of diagnostic products.