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Downstream Manufacturing Scientist

Astrix
locationMiddlesex County, NJ, USA
PublishedPublished: 6/14/2022
Manufacturing
Full Time

Job Description

Opportunity for an experienced Downstream Manufacturing Technician (multiple levels) to continue their career in downstream/upstream manufacturing. This role will be with our client who has a global footprint in both R&D and manufacturing within the biopharma industry.


Location: Middlesex County NJ

Direct Hire: 60,000-90,000 DOE

Schedule: M-F 1st shift (needs to be flexible to 2nd & 3rd Shift)

Column Chromatography experience required


Essential Duties & Responsibilities

  • Perform downstream processing at various scales in a cGMP environment, including column packing, process troubleshooting, and data analysis.
  • Provide technical guidance in the execution and development of purification processes.
  • Utilize systems to collect and analyze operational data and make real-time adjustments to products, instruments, or equipment.
  • Ensure timely execution of engineering and clinical batches.
  • Develop equipment operating specifications and enhance manufacturing techniques.
  • Collaborate with other teams and external vendors to address technical challenges and maintain production equipment.
  • Follow GMP guidelines in the manufacturing area and lead efforts to uphold environmental health and safety policies.
  • Oversee investigations and corrective actions for issues identified during batch execution.
  • Perform additional tasks as assigned.
  • Comply with all company policies and operational standards.


Requirements

Education and Experience

  • Bachelor’s or Master’s degree in chemical, biological, or biochemical sciences with 1-3 years of relevant experience in the biopharmaceutical industry.
  • Experience working in GMP and aseptic manufacturing environments.
  • Proficiency in operating systems like AKTA Process skids (or similar) and familiarity with single-use manufacturing consumables, including bags, tube sets, columns, and process manifolds.
  • Knowledge and experience in executing engineering and clinical batches, as well as familiarity with GMP documentation.

Special Skills

  • Ability to collaborate with team members and work independently; strong interpersonal skills.
  • Excellent verbal and written communication skills; strong organizational skills and attention to detail.
  • Basic computer proficiency, including knowledge of Word, Excel, and spreadsheets.
  • Expertise in GMP batch manufacturing and packaging documentation, including auditing and review processes.
  • Familiarity with cleaning verification and validation processes.


This job description is a complete list of all desired skills, but not all are required. We strongly encourage candidates who have some of the skills to apply. We look forward to a conversation to learn more about you!

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