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RA/SRA - Next Generation Sequencing

companyOrna Therapeutics
locationCambridge, MA, USA
PublishedPublished: 6/14/2022
Full Time

We are seeking a highly motivated and detail-oriented Research Associate / Senior Research Associate to join our dynamic team at Orna, a leading biotech company focused on bringing our cutting edge technologies in RNA medicines and lipid delivery to multiple fields, including gene editing. The successful candidate will play a crucial role in our next-generation sequencing (NGS) efforts to advance gene editing projects and support a wide range of discovery work at the company.

Key Responsibilities

  • Work in a team environment to design, coordinate, and execute NGS-based experiments to support gene editing projects and other efforts at the company
  • Perform all steps of NGS sequencing protocols, including DNA/RNA extraction, library preparation, sequencing.
  • Collaborate with cross-functional teams to integrate NGS data with gene editing strategies.
  • Maintain accurate and detailed records of experiments and results.
  • Present findings in team meetings and contribute to scientific publications and patent applications.
  • Stay current with advancements in NGS and gene editing technologies through literature review and participation in scientific conferences.

Qualifications

  • Bachelor's or Master's degree in Molecular Biology, Genetics, Biochemistry, or a related field.
  • 2+ years of hands-on experience with molecular biology techniques.
  • Proficiency in nucleic acid molecular biology, such as DNA/RNA extraction and purification, preparation of samples for PCR/qPCR/NGS, or plasmid construction.
  • Familiarity with bioinformatics tools and data analysis software.
  • Strong analytical and problem-solving skills.
  • Excellent organizational and communication skills.
  • Ability to work independently and collaboratively in a fast-paced environment.

Preferred Qualifications

  • Proficiency in NGS protocol design, library preparation and QC, and sequencer operation.
  • Experience with CRISPR/Cas9 or other gene editing technologies.
  • Knowledge of regulatory guidelines and quality control standards in NGS.
  • Experience with high-throughput sequencing platforms (e.g., Illumina, PacBio, Oxford Nanopore).

Benefits

  • Competitive salary and benefits package.
  • Opportunities for professional development and career advancement.
  • Collaborative and innovative work environment.
  • Access to state-of-the-art facilities and cutting-edge technologies.
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